Anti-NAB2 antibody (1-200) (STJ28390)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal NAB2 (1-200) antibody for use in WB and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | NAB2 |
| Gene ID | 4665 |
| Uniprot ID | NAB2_HUMAN |
| Immunogen Region | 1-200 |
| Immunogen Sequence | MHRAPSPTAEQPPGGGDSAR RTLQPRLKPSARAMALPRTL GELQLYRVLQRANLLSYYET FIQQGGDDVQQLCEAGEEEF LEIMALVGMATKPLHVRRLQ KALREWATNPGLFSQPVPAV PVSSIPLFKISETAGTRKGS MSNGHGSPGEKAGSARSFSP KSPLELGEKLSPLPGGPGAG DPRIWPGRSTPESDVGAGGE |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human NAB2 (NP_005958.1). |
Additional Info
| Tissue Specificity | Widely expressed at low levels. Highly expressed in melanoma cell lines. |
| Post Translational Modifications | Sumoylation by EGR2 represses EGR2 transcriptional activity in hindbrain. |
| Function | Acts as a transcriptional repressor for zinc finger transcription factors EGR1 and EGR2. Isoform 2 lacks repression ability. |
| Protein Name | Ngfi-A-Binding Protein 2Egr-1-Binding Protein 2Melanoma-Associated Delayed Early Response ProteinProtein Mader |
| Database Links | Reactome: R-HSA-9031628Reactome: R-HSA-9619665 |
| Cellular Localisation | NucleusIsoform 2 Is Not Localized To The Nucleus |
| Alternative Antibody Names | Anti-Ngfi-A-Binding Protein 2 antibodyAnti-Egr-1-Binding Protein 2 antibodyAnti-Melanoma-Associated Delayed Early Response Protein antibodyAnti-Protein Mader antibodyAnti-NAB2 antibodyAnti-MADER antibody |
Information sourced from Uniprot.org