Host: |
Rabbit |
Applications: |
WB |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-MYT1 (650-820) is suitable for use in Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:500-1:2000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
MYT1 |
Gene ID: |
4661 |
Uniprot ID: |
MYT1_HUMAN |
Immunogen Region: |
650-820 |
Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 650-820 of human MYT1 (NP_004526.1). |
Immunogen Sequence: |
KPQDLPSKSVDIEVDENGTL DLSMHKHRKRENAFPSSSSC SSSPGVKSPDASQRHSSTSA PSSSMTSPQSSQASRQDEWD RPLDYTKPSRLREEEPEESE PAAHSFASSEADDQEVSEEN FEERKYPGEVTLTNFKLKFL SKDIKKELLTCPTPGCDGSG HITGNYASHRS |
Tissue Specificity | Mostly in developing nervous system. Expressed in neural progenitors and oligodendrocyte lineage cells. More highly expressed in oligodendrocyte progenitors than in differentiated oligodendrocytes. |
Function | Binds to the promoter region of genes encoding proteolipid proteins of the central nervous system. May play a role in the development of neurons and oligodendroglia in the CNS. May regulate a critical transition point in oligodendrocyte lineage development by modulating oligodendrocyte progenitor proliferation relative to terminal differentiation and up-regulation of myelin gene transcription. |
Protein Name | Myelin Transcription Factor 1Myt1Myelin Transcription Factor IMytiPlpb1Proteolipid Protein-Binding Protein |
Cellular Localisation | Nucleus |
Alternative Antibody Names | Anti-Myelin Transcription Factor 1 antibodyAnti-Myt1 antibodyAnti-Myelin Transcription Factor I antibodyAnti-Myti antibodyAnti-Plpb1 antibodyAnti-Proteolipid Protein-Binding Protein antibodyAnti-MYT1 antibodyAnti-KIAA0835 antibodyAnti-KIAA1050 antibodyAnti-MTF1 antibodyAnti-MYTI antibodyAnti-PLPB1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance