Western blot analysis of various lysates using MYT1 Rabbit polyclonal antibody (STJ112720) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 5s.

Anti-MYT1 antibody (650-820) (STJ112720)

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STJ112720
£112.50 - £524.50
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Host: Rabbit
Applications: WB/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:2000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: MYT1
Gene ID: 4661
Uniprot ID: MYT1_HUMAN
Immunogen Region: 650-820
Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 650-820 of human MYT1 (NP_004526.1).
Immunogen Sequence: KPQDLPSKSVDIEVDENGTL DLSMHKHRKRENAFPSSSSC SSSPGVKSPDASQRHSSTSA PSSSMTSPQSSQASRQDEWD RPLDYTKPSRLREEEPEESE PAAHSFASSEADDQEVSEEN FEERKYPGEVTLTNFKLKFL SKDIKKELLTCPTPGCDGSG HITGNYASHRS
Tissue Specificity Mostly in developing nervous system. Expressed in neural progenitors and oligodendrocyte lineage cells. More highly expressed in oligodendrocyte progenitors than in differentiated oligodendrocytes.
Function Binds to the promoter region of genes encoding proteolipid proteins of the central nervous system. May play a role in the development of neurons and oligodendroglia in the CNS. May regulate a critical transition point in oligodendrocyte lineage development by modulating oligodendrocyte progenitor proliferation relative to terminal differentiation and up-regulation of myelin gene transcription.
Protein Name Myelin Transcription Factor 1
Myt1
Myelin Transcription Factor I
Myti
Plpb1
Proteolipid Protein-Binding Protein
Cellular Localisation Nucleus
Alternative Antibody Names Anti-Myelin Transcription Factor 1 antibody
Anti-Myt1 antibody
Anti-Myelin Transcription Factor I antibody
Anti-Myti antibody
Anti-Plpb1 antibody
Anti-Proteolipid Protein-Binding Protein antibody
Anti-MYT1 antibody
Anti-KIAA0835 antibody
Anti-KIAA1050 antibody
Anti-MTF1 antibody
Anti-MYTI antibody
Anti-PLPB1 antibody

Information sourced from Uniprot.org

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