| Short Description : | Rabbit polyclonal MYT1 (650-820) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | MYT1 |
| Gene ID: | 4661 |
| Uniprot ID: | MYT1_HUMAN |
| Immunogen Region: | 650-820 |
| Immunogen Sequence: | KPQDLPSKSVDIEVDENGTL DLSMHKHRKRENAFPSSSSC SSSPGVKSPDASQRHSSTSA PSSSMTSPQSSQASRQDEWD RPLDYTKPSRLREEEPEESE PAAHSFASSEADDQEVSEEN FEERKYPGEVTLTNFKLKFL SKDIKKELLTCPTPGCDGSG HITGNYASHRS |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 650-820 of human MYT1 (NP_004526.1). |
| Tissue Specificity | Mostly in developing nervous system. Expressed in neural progenitors and oligodendrocyte lineage cells. More highly expressed in oligodendrocyte progenitors than in differentiated oligodendrocytes. |
| Function | Binds to the promoter region of genes encoding proteolipid proteins of the central nervous system. May play a role in the development of neurons and oligodendroglia in the CNS. May regulate a critical transition point in oligodendrocyte lineage development by modulating oligodendrocyte progenitor proliferation relative to terminal differentiation and up-regulation of myelin gene transcription. |
| Protein Name | Myelin Transcription Factor 1Myt1Myelin Transcription Factor IMytiPlpb1Proteolipid Protein-Binding Protein |
| Database Links | |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Myelin Transcription Factor 1 antibodyAnti-Myt1 antibodyAnti-Myelin Transcription Factor I antibodyAnti-Myti antibodyAnti-Plpb1 antibodyAnti-Proteolipid Protein-Binding Protein antibodyAnti-MYT1 antibodyAnti-KIAA0835 antibodyAnti-KIAA1050 antibodyAnti-MTF1 antibodyAnti-MYTI antibodyAnti-PLPB1 antibody |
Information sourced from Uniprot.org
![Immunohistochemistry analysis of paraffin-embedded human esophageal cancer using [KO Validated] NCOA2 Rabbit polyclonal antibody (STJ112318) at dilution of 1:100 (40x lens). Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6. 0 before commencing with immunohistochemistry staining protocol.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/600x533/products/92369/372743/STJ112318_1__72291.1713138814.jpg?c=1 "Immunohistochemistry analysis of paraffin-embedded human esophageal cancer using [KO Validated] NCOA2 Rabbit polyclonal antibody (STJ112318) at dilution of 1:100 (40x lens). Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6. 0 before commencing with immunohistochemistry staining protocol.")
