Anti-MUC6 antibody (1000-1100 aa) [ABT351] (STJ190075)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG2ak
ImmunogenSynthesized peptide derived from the human MUC6 at the amino acid range 1000-1100
General Information
| Short Description | Mouse monoclonal anti-Mucin-6 (1000-1100 aa) for use in IHC in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC |
| Host | Mouse |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | ABT351 |
| Isotype | IgG2ak |
| Conjugation | Unconjugated |
| Purification | The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. |
| Dilution Range | IHC-P 1:200-400 |
| Formulation | Liquid in PBS pH7.2, 0.03% Proclin 300, with stabilizing protein. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MUC6 |
| Gene ID | 4588 |
| Uniprot ID | MUC6_HUMAN |
| Immunogen | Synthesized peptide derived from the human MUC6 at the amino acid range 1000-1100 |
| Immunogen Region | 1000-1100 aa |
| Specificity | The antibody can specifically recognize human MUC6 protein.. The antibody was also Predict react with Mouse;Rat |
Additional Info
| Post Translational Modifications | O-glycosylated. |
| Function | May provide a mechanism for modulation of the composition of the protective mucus layer related to acid secretion or the presence of bacteria and noxious agents in the lumen. Plays an important role in the cytoprotection of epithelial surfaces and are used as tumor markers in a variety of cancers. May play a role in epithelial organogenesis. |
| Protein Name | Mucin-6Muc-6Gastric Mucin-6 |
| Database Links | Reactome: R-HSA-5083625Reactome: R-HSA-5083632Reactome: R-HSA-5083636Reactome: R-HSA-5621480Reactome: R-HSA-913709Reactome: R-HSA-977068 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Mucin-6 antibodyAnti-Muc-6 antibodyAnti-Gastric Mucin-6 antibodyAnti-MUC6 antibody |
Information sourced from Uniprot.org