| Host: |
Mouse |
| Applications: |
IHC |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Mouse monoclonal antibody anti-Mucin-6 (1000-1100 aa) is suitable for use in Immunohistochemistry research applications. |
| Clonality: |
Monoclonal |
| Clone ID: |
ABT351 |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG2ak |
| Formulation: |
Liquid in PBS pH7.2, 0.03% Proclin 300, with stabilizing protein. |
| Purification: |
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. |
| Dilution Range: |
IHC-P 1:200-400 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
MUC6 |
| Gene ID: |
4588 |
| Uniprot ID: |
MUC6_HUMAN |
| Immunogen Region: |
1000-1100 aa |
| Specificity: |
The antibody can specifically recognize human MUC6 protein.. The antibody was also Predict react with Mouse;Rat |
| Immunogen: |
Synthesized peptide derived from the human MUC6 at the amino acid range 1000-1100 |
| Post Translational Modifications | O-glycosylated. |
| Function | May provide a mechanism for modulation of the composition of the protective mucus layer related to acid secretion or the presence of bacteria and noxious agents in the lumen. Plays an important role in the cytoprotection of epithelial surfaces and are used as tumor markers in a variety of cancers. May play a role in epithelial organogenesis. |
| Protein Name | Mucin-6Muc-6Gastric Mucin-6 |
| Database Links | Reactome: R-HSA-5083625Reactome: R-HSA-5083632Reactome: R-HSA-5083636Reactome: R-HSA-5621480Reactome: R-HSA-913709Reactome: R-HSA-977068 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Mucin-6 antibodyAnti-Muc-6 antibodyAnti-Gastric Mucin-6 antibodyAnti-MUC6 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
