| Post Translational Modifications | Phosphorylated by CDK1 during mitosis. |
| Function | Lipid phosphatase that specifically dephosphorylates the D-3 position of phosphatidylinositol 3-phosphate and phosphatidylinositol 3,5-bisphosphate, generating phosphatidylinositol and phosphatidylinositol 5-phosphate. Decreases the levels of phosphatidylinositol 3-phosphate, a phospholipid found in cell membranes where it acts as key regulator of both cell signaling and intracellular membrane traffic. Could also have a molecular sequestering/adapter activity and regulate biological processes independently of its phosphatase activity. It includes the regulation of midbody abscission during mitotic cytokinesis. |
| Protein Name | Phosphatidylinositol-3 -5-Bisphosphate 3-Phosphatase Mtmr3Fyve Domain-Containing Dual Specificity Protein Phosphatase 1Fyve-Dsp1Myotubularin-Related Protein 3Phosphatidylinositol-3 -5-Bisphosphate 3-PhosphatasePhosphatidylinositol-3-Phosphate PhosphataseZinc Finger Fyve Domain-Containing Protein 10 |
| Database Links | Reactome: R-HSA-1632852Reactome: R-HSA-1660499 |
| Cellular Localisation | CytoplasmCytosolMembranePeripheral Membrane Protein |
| Alternative Antibody Names | Anti-Phosphatidylinositol-3 -5-Bisphosphate 3-Phosphatase Mtmr3 antibodyAnti-Fyve Domain-Containing Dual Specificity Protein Phosphatase 1 antibodyAnti-Fyve-Dsp1 antibodyAnti-Myotubularin-Related Protein 3 antibodyAnti-Phosphatidylinositol-3 -5-Bisphosphate 3-Phosphatase antibodyAnti-Phosphatidylinositol-3-Phosphate Phosphatase antibodyAnti-Zinc Finger Fyve Domain-Containing Protein 10 antibodyAnti-MTMR3 antibodyAnti-KIAA0371 antibodyAnti-ZFYVE10 antibody |
Information sourced from Uniprot.org
