| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: |
Affinity purification |
| Concentration: |
Lot specific |
| Dilution Range: |
WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
MTMR3 |
| Gene ID: |
8897 |
| Uniprot ID: |
MTMR3_HUMAN |
| Immunogen Region: |
640-810 |
| Specificity: |
Recombinant fusion protein containing a sequence corresponding to amino acids 640-810 of human MTMR3 (NP_066576.1). |
| Immunogen Sequence: |
KWQEHRRSLELSSLAGPGED PLSADSLGKPTRVPGGAELS VAAGVAEGQMENILQEATKE ESGVEEPAHRAGIEIQEGKE DPLLEKESRRKTPEASAIGL HQDPELGDAALRSHLDMSWP LFSQGISEQQSGLSVLLSSL QVPPRGEDSLEVPVEQFRIE EIAEGREEAVL |
| Post Translational Modifications | Phosphorylated by CDK1 during mitosis. |
| Function | Lipid phosphatase that specifically dephosphorylates the D-3 position of phosphatidylinositol 3-phosphate and phosphatidylinositol 3,5-bisphosphate, generating phosphatidylinositol and phosphatidylinositol 5-phosphate. Decreases the levels of phosphatidylinositol 3-phosphate, a phospholipid found in cell membranes where it acts as key regulator of both cell signaling and intracellular membrane traffic. Could also have a molecular sequestering/adapter activity and regulate biological processes independently of its phosphatase activity. It includes the regulation of midbody abscission during mitotic cytokinesis. |
| Protein Name | Phosphatidylinositol-3 -5-Bisphosphate 3-Phosphatase Mtmr3Fyve Domain-Containing Dual Specificity Protein Phosphatase 1Fyve-Dsp1Myotubularin-Related Protein 3Phosphatidylinositol-3 -5-Bisphosphate 3-PhosphatasePhosphatidylinositol-3-Phosphate PhosphataseZinc Finger Fyve Domain-Containing Protein 10 |
| Database Links | Reactome: R-HSA-1632852Reactome: R-HSA-1660499 |
| Cellular Localisation | CytoplasmCytosolMembranePeripheral Membrane Protein |
| Alternative Antibody Names | Anti-Phosphatidylinositol-3 -5-Bisphosphate 3-Phosphatase Mtmr3 antibodyAnti-Fyve Domain-Containing Dual Specificity Protein Phosphatase 1 antibodyAnti-Fyve-Dsp1 antibodyAnti-Myotubularin-Related Protein 3 antibodyAnti-Phosphatidylinositol-3 -5-Bisphosphate 3-Phosphatase antibodyAnti-Phosphatidylinositol-3-Phosphate Phosphatase antibodyAnti-Zinc Finger Fyve Domain-Containing Protein 10 antibodyAnti-MTMR3 antibodyAnti-KIAA0371 antibodyAnti-ZFYVE10 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
