Anti-MGAT4A antibody (28-100) (STJ117596)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal MGAT4A (28-100) antibody for use in WB and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:200-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MGAT4A |
| Gene ID | 11320 |
| Uniprot ID | MGT4A_HUMAN |
| Immunogen Region | 28-100 |
| Immunogen Sequence | QNGKEKLIAYQREFLALKER LRIAEHRISQRSSELNTIVQ QFKRVGAETNGSKDALNKFS DNTLKLLKELTSK |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 28-100 of human MGAT4A (NP_036346.1). |
Additional Info
| Tissue Specificity | Expressed in pancreas, spleen, thymus, prostate, small intestine, peripheral blood leukocytes and lymph node. Strongly overexpressed in choriocarcinoma cancer cell lines. Down-regulated in pancreatic cancer. |
| Post Translational Modifications | N-glycosylated. |
| Function | Glycosyltransferase that catalyze the transfer of GlcNAc from UDP-GlcNAc to the GlcNAcbeta1-2Manalpha1-3 arm of the core structure of N-linked glycans through a beta1-4 linkage and participates in the production of tri- and tetra-antennary N-linked sugar chains. Involved in glucose transport by mediating SLC2A2/GLUT2 glycosylation, thereby controlling cell-surface expression of SLC2A2 in pancreatic beta cells. |
| Protein Name | Alpha-1 -3-Mannosyl-Glycoprotein 4-Beta-N-Acetylglucosaminyltransferase AN-Glycosyl-Oligosaccharide-Glycoprotein N-Acetylglucosaminyltransferase IvaGlcnac-T IvaGnt-IvaN-Acetylglucosaminyltransferase IvaUdp-N-Acetylglucosamine - Alpha-1 -3-D-Mannoside Beta-1 -4-N-Acetylglucosaminyltransferase Iva Cleaved Into - Alpha-1 -3-Mannosyl-Glycoprotein 4-Beta-N-Acetylglucosaminyltransferase A Soluble Form |
| Database Links | Reactome: R-HSA-381426Reactome: R-HSA-8957275Reactome: R-HSA-9694548Reactome: R-HSA-975577 |
| Cellular Localisation | Alpha-13-Mannosyl-Glycoprotein 4-Beta-N-Acetylglucosaminyltransferase A: Golgi Apparatus MembraneSingle-Pass Type Ii Membrane Protein3-Mannosyl-Glycoprotein 4-Beta-N-Acetylglucosaminyltransferase A Soluble Form: Secreted |
| Alternative Antibody Names | Anti-Alpha-1 -3-Mannosyl-Glycoprotein 4-Beta-N-Acetylglucosaminyltransferase A antibodyAnti-N-Glycosyl-Oligosaccharide-Glycoprotein N-Acetylglucosaminyltransferase Iva antibodyAnti-Glcnac-T Iva antibodyAnti-Gnt-Iva antibodyAnti-N-Acetylglucosaminyltransferase Iva antibodyAnti-Udp-N-Acetylglucosamine - Alpha-1 -3-D-Mannoside Beta-1 -4-N-Acetylglucosaminyltransferase Iva Cleaved Into - Alpha-1 -3-Mannosyl-Glycoprotein 4-Beta-N-Acetylglucosaminyltransferase A Soluble Form antibodyAnti-MGAT4A antibody |
Information sourced from Uniprot.org