| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-MGAT4A (28-100) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:200-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
MGAT4A |
| Gene ID: |
11320 |
| Uniprot ID: |
MGT4A_HUMAN |
| Immunogen Region: |
28-100 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 28-100 of human MGAT4A (NP_036346.1). |
| Immunogen Sequence: |
QNGKEKLIAYQREFLALKER LRIAEHRISQRSSELNTIVQ QFKRVGAETNGSKDALNKFS DNTLKLLKELTSK |
| Tissue Specificity | Expressed in pancreas, spleen, thymus, prostate, small intestine, peripheral blood leukocytes and lymph node. Strongly overexpressed in choriocarcinoma cancer cell lines. Down-regulated in pancreatic cancer. |
| Post Translational Modifications | N-glycosylated. |
| Function | Glycosyltransferase that catalyze the transfer of GlcNAc from UDP-GlcNAc to the GlcNAcbeta1-2Manalpha1-3 arm of the core structure of N-linked glycans through a beta1-4 linkage and participates in the production of tri- and tetra-antennary N-linked sugar chains. Involved in glucose transport by mediating SLC2A2/GLUT2 glycosylation, thereby controlling cell-surface expression of SLC2A2 in pancreatic beta cells. |
| Protein Name | Alpha-1 -3-Mannosyl-Glycoprotein 4-Beta-N-Acetylglucosaminyltransferase AN-Glycosyl-Oligosaccharide-Glycoprotein N-Acetylglucosaminyltransferase IvaGlcnac-T IvaGnt-IvaN-Acetylglucosaminyltransferase IvaUdp-N-Acetylglucosamine - Alpha-1 -3-D-Mannoside Beta-1 -4-N-Acetylglucosaminyltransferase Iva Cleaved Into - Alpha-1 -3-Mannosyl-Glycoprotein 4-Beta-N-Acetylglucosaminyltransferase A Soluble Form |
| Database Links | Reactome: R-HSA-381426Reactome: R-HSA-8957275Reactome: R-HSA-9694548Reactome: R-HSA-975577 |
| Cellular Localisation | Alpha-13-Mannosyl-Glycoprotein 4-Beta-N-Acetylglucosaminyltransferase A: Golgi Apparatus MembraneSingle-Pass Type Ii Membrane Protein3-Mannosyl-Glycoprotein 4-Beta-N-Acetylglucosaminyltransferase A Soluble Form: Secreted |
| Alternative Antibody Names | Anti-Alpha-1 -3-Mannosyl-Glycoprotein 4-Beta-N-Acetylglucosaminyltransferase A antibodyAnti-N-Glycosyl-Oligosaccharide-Glycoprotein N-Acetylglucosaminyltransferase Iva antibodyAnti-Glcnac-T Iva antibodyAnti-Gnt-Iva antibodyAnti-N-Acetylglucosaminyltransferase Iva antibodyAnti-Udp-N-Acetylglucosamine - Alpha-1 -3-D-Mannoside Beta-1 -4-N-Acetylglucosaminyltransferase Iva Cleaved Into - Alpha-1 -3-Mannosyl-Glycoprotein 4-Beta-N-Acetylglucosaminyltransferase A Soluble Form antibodyAnti-MGAT4A antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
