Host: |
Rabbit |
Applications: |
WB/IHC |
Reactivity: |
Human/Mouse |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit monoclonal antibody anti-MEF2A+MEF2C (250-473) is suitable for use in Western Blot and Immunohistochemistry research applications. |
Clonality: |
Monoclonal |
Clone ID: |
S4MR |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:500-1:1000IHC-P 1:50-1:200 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Immunogen Region: |
250-473 |
Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 250-473 of human MEF2A+MEF2C (Q06413). |
Immunogen Sequence: |
NRKPDLRVLIPPGSKNTMPS VSEDVDLLLNQRINNSQSAQ SLATPVVSVATPTLPGQGMG GYPSAISTTYGTEYSLSSAD LSSLSGFNTASALHLGSVTG WQQQHLHNMPPSALSQLGAC TSTHLSQSSNLSLPSTQSLN IKSEPVSPPRDRTTTPSRYP QHTRHEAGRSPVDSLSSCSS SYDGSDREDHRNEFHSPIGL TRPSPDERESPSVKRMRLSE GWAT |
Background | The protein encoded by this gene belongs to the basic helix-loop-helix family of transcription factors. This gene product is one of two closely related family members, the HAND proteins, which are asymmetrically expressed in the developing ventricular chambers and play an essential role in cardiac morphogenesis. Working in a complementary fashion, they function in the formation of the right ventricle and aortic arch arteries, implicating them as mediators of congenital heart disease. In addition, this transcription factor plays an important role in limb and branchial arch development. |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance