| Host: | Mouse |
| Applications: | WB/FC/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Mouse monoclonal antibody anti-Megakaryocyte-associated tyrosine-protein kinase is suitable for use in Western Blot, Flow Cytometry and ELISA research applications. |
| Clonality : | Monoclonal |
| Clone ID : | 9D7 |
| Conjugation: | Unconjugated |
| Isotype: | IgG1 |
| Formulation: | Liquid in PBS containing 50% Glycerol and 0.03% Sodium Azide. |
| Purification: | Antibody are purified by protein G affinity chromatography. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-1:2000 FC 1:200-1:400 ELISA 1:10000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | MATK |
| Gene ID: | 4145 |
| Uniprot ID: | MATK_HUMAN |
| Specificity: | Lsk Monoclonal Antibody detects endogenous levels of Lsk protein. |
| Immunogen: | Purified recombinant fragment of human Lsk expressed in E. Coli. |
| Function | Could play a significant role in the signal transduction of hematopoietic cells. May regulate tyrosine kinase activity of SRC-family members in brain by specifically phosphorylating their C-terminal regulatory tyrosine residue which acts as a negative regulatory site. It may play an inhibitory role in the control of T-cell proliferation. |
| Protein Name | Megakaryocyte-Associated Tyrosine-Protein Kinase Csk Homologous Kinase Chk Hematopoietic Consensus Tyrosine-Lacking Kinase Protein Kinase Hyl Tyrosine-Protein Kinase Ctk |
| Database Links | Reactome: R-HSA-8863795 |
| Cellular Localisation | Cytoplasm Membrane In Platelets 90% Of Matk Localizes To The Membrane Fraction And Translocates To The Cytoskeleton Upon Thrombin Stimulation |
| Alternative Antibody Names | Anti-Megakaryocyte-Associated Tyrosine-Protein Kinase antibody Anti-Csk Homologous Kinase antibody Anti-Chk antibody Anti-Hematopoietic Consensus Tyrosine-Lacking Kinase antibody Anti-Protein Kinase Hyl antibody Anti-Tyrosine-Protein Kinase Ctk antibody Anti-MATK antibody Anti-CTK antibody Anti-HYL antibody |
Information sourced from Uniprot.org