Host: |
Mouse |
Applications: |
WB/FC/ELISA |
Reactivity: |
Human |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Mouse monoclonal antibody anti-Megakaryocyte-associated tyrosine-protein kinase is suitable for use in Western Blot, Flow Cytometry and ELISA research applications. |
Clonality: |
Monoclonal |
Clone ID: |
9D7 |
Conjugation: |
Unconjugated |
Isotype: |
IgG1 |
Formulation: |
Liquid in PBS containing 50% Glycerol and 0.03% Sodium Azide. |
Purification: |
Antibody are purified by protein G affinity chromatography. |
Concentration: |
1 mg/mL |
Dilution Range: |
WB 1:500-1:2000FC 1:200-1:400ELISA 1:10000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
MATK |
Gene ID: |
4145 |
Uniprot ID: |
MATK_HUMAN |
Specificity: |
Lsk Monoclonal Antibody detects endogenous levels of Lsk protein. |
Immunogen: |
Purified recombinant fragment of human Lsk expressed in E. Coli. |
Function | Could play a significant role in the signal transduction of hematopoietic cells. May regulate tyrosine kinase activity of SRC-family members in brain by specifically phosphorylating their C-terminal regulatory tyrosine residue which acts as a negative regulatory site. It may play an inhibitory role in the control of T-cell proliferation. |
Protein Name | Megakaryocyte-Associated Tyrosine-Protein KinaseCsk Homologous KinaseChkHematopoietic Consensus Tyrosine-Lacking KinaseProtein Kinase HylTyrosine-Protein Kinase Ctk |
Database Links | Reactome: R-HSA-8863795 |
Cellular Localisation | CytoplasmMembraneIn Platelets90% Of Matk Localizes To The Membrane FractionAnd Translocates To The Cytoskeleton Upon Thrombin Stimulation |
Alternative Antibody Names | Anti-Megakaryocyte-Associated Tyrosine-Protein Kinase antibodyAnti-Csk Homologous Kinase antibodyAnti-Chk antibodyAnti-Hematopoietic Consensus Tyrosine-Lacking Kinase antibodyAnti-Protein Kinase Hyl antibodyAnti-Tyrosine-Protein Kinase Ctk antibodyAnti-MATK antibodyAnti-CTK antibodyAnti-HYL antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance