Anti-KMT2C antibody (STJA0008056)

SKU:
STJA0008056
$67.62 - $360.18
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Short Description :Rabbit polyclonal anti-Histone-lysine N-methyltransferase 2C for use in WB in Human samples. Datasheet included with dilution recommendations, and related reagents.
Applications:WB
Host:Rabbit
Reactivity:Human
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Polyclonal
Isotype:IgG
Conjugation:Unconjugated
Concentration:1 mg/mL
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Dilution Range:WB 1:500-2000
Formulation:Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage Instruction:Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol:KMT2C
Gene ID:58508
Uniprot ID:KMT2C_HUMAN
Immunogen:Synthesized peptide derived from human KMT2C
Specificity:This antibody detects endogenous levels of KMT2C at Human
Function Histone methyltransferase that catalyzes methyl group transfer from S-adenosyl-L-methionine to the epsilon-amino group of 'Lys-4' of histone H3 (H3K4). Part of chromatin remodeling machinery predominantly forms H3K4me1 methylation marks at active chromatin sites where transcription and DNA repair take place. Likely plays a redundant role with KMT2D in enriching H3K4me1 mark on primed and active enhancer elements.
Protein Name Histone-Lysine N-Methyltransferase 2c
Lysine N-Methyltransferase 2c
Homologous To Alr Protein
Myeloid/Lymphoid Or Mixed-Lineage Leukemia Protein 3
Database Links Reactome: R-HSA-3214841
Reactome: R-HSA-5617472
Reactome: R-HSA-8936459
Reactome: R-HSA-9772755
Reactome: R-HSA-9818564
Reactome: R-HSA-9841922
Cellular Localisation Nucleus
Alternative Antibody Names Anti-Histone-Lysine N-Methyltransferase 2c antibody
Anti-Lysine N-Methyltransferase 2c antibody
Anti-Homologous To Alr Protein antibody
Anti-Myeloid/Lymphoid Or Mixed-Lineage Leukemia Protein 3 antibody
Anti-KMT2C antibody
Anti-HALR antibody
Anti-KIAA1506 antibody
Anti-MLL3 antibody

Information sourced from Uniprot.org