Anti-KMT2C antibody (STJA0008056)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human KMT2C
General Information
| Short Description | Rabbit polyclonal anti-Histone-lysine N-methyltransferase 2C for use in WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | KMT2C |
| Gene ID | 58508 |
| Uniprot ID | KMT2C_HUMAN |
| Immunogen | Synthesized peptide derived from human KMT2C |
| Specificity | This antibody detects endogenous levels of KMT2C at Human |
Additional Info
| Function | Histone methyltransferase that catalyzes methyl group transfer from S-adenosyl-L-methionine to the epsilon-amino group of 'Lys-4' of histone H3 (H3K4). Part of chromatin remodeling machinery predominantly forms H3K4me1 methylation marks at active chromatin sites where transcription and DNA repair take place. Likely plays a redundant role with KMT2D in enriching H3K4me1 mark on primed and active enhancer elements. |
| Protein Name | Histone-Lysine N-Methyltransferase 2cLysine N-Methyltransferase 2cHomologous To Alr ProteinMyeloid/Lymphoid Or Mixed-Lineage Leukemia Protein 3 |
| Database Links | Reactome: R-HSA-3214841Reactome: R-HSA-5617472Reactome: R-HSA-8936459Reactome: R-HSA-9772755Reactome: R-HSA-9818564Reactome: R-HSA-9841922 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Histone-Lysine N-Methyltransferase 2c antibodyAnti-Lysine N-Methyltransferase 2c antibodyAnti-Homologous To Alr Protein antibodyAnti-Myeloid/Lymphoid Or Mixed-Lineage Leukemia Protein 3 antibodyAnti-KMT2C antibodyAnti-HALR antibodyAnti-KIAA1506 antibodyAnti-MLL3 antibody |
Information sourced from Uniprot.org