Function | Histone methyltransferase that catalyzes methyl group transfer from S-adenosyl-L-methionine to the epsilon-amino group of 'Lys-4' of histone H3 (H3K4). Part of chromatin remodeling machinery predominantly forms H3K4me1 methylation marks at active chromatin sites where transcription and DNA repair take place. Likely plays a redundant role with KMT2D in enriching H3K4me1 mark on primed and active enhancer elements. |
Protein Name | Histone-Lysine N-Methyltransferase 2cLysine N-Methyltransferase 2cHomologous To Alr ProteinMyeloid/Lymphoid Or Mixed-Lineage Leukemia Protein 3 |
Database Links | Reactome: R-HSA-3214841Reactome: R-HSA-5617472Reactome: R-HSA-8936459Reactome: R-HSA-9772755 |
Cellular Localisation | Nucleus |
Alternative Antibody Names | Anti-Histone-Lysine N-Methyltransferase 2c antibodyAnti-Lysine N-Methyltransferase 2c antibodyAnti-Homologous To Alr Protein antibodyAnti-Myeloid/Lymphoid Or Mixed-Lineage Leukemia Protein 3 antibodyAnti-KMT2C antibodyAnti-HALR antibodyAnti-KIAA1506 antibodyAnti-MLL3 antibody |
Information sourced from Uniprot.org