Anti-KIR2DL3 antibody (22-245) (STJ24316)

SKU:
STJ24316
£110.50 - £505.50
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Applications:WB/IF/ICC/ELISA
Host:Rabbit
Reactivity:Human/Mouse
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Polyclonal
Isotype:IgG
Conjugation:Unconjugated
Concentration:Lot specific
Purification:Affinity purification
Dilution Range:WB:1:500-1:2000
IF/ICC:1:50-1:200
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Formulation:PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3.
Storage Instruction:Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol:KIR2DL3
Gene ID:3804
Uniprot ID:KI2L3_HUMAN
Immunogen Region:22-245
Immunogen Sequence:HEGVHRKPSLLAHPGPLVKS EETVILQCWSDVRFQHFLLH REGKFKDTLHLIGEHHDGVS KANFSIGPMMQDLAGTYRCY GSVTHSPYQLSAPSDPLDIV ITGLYEKPSLSAQPGPTVLA GESVTLSCSSRSSYDMYHLS REGEAHERRFSAGPKVNGTF QADFPLGPATHGGTYRCFGS FRDSPYEWSNSSDPLLVSVT GNPSNSWPSPTEPSSETGNP RHLH
Specificity:Recombinant fusion protein containing a sequence corresponding to amino acids 22-245 of human KIR2DL3 (NP_056952.2).
Function Receptor on natural killer (NK) cells for HLA-C alleles (HLA-Cw1, HLA-Cw3 and HLA-Cw7). Inhibits the activity of NK cells thus preventing cell lysis.
Protein Name Killer Cell Immunoglobulin-Like Receptor 2dl3
Cd158 Antigen-Like Family Member B2
Kir-023gb
Killer Inhibitory Receptor Cl 2-3
Nkat2a
Nkat2b
Natural Killer-Associated Transcript 2
Nkat-2
P58 Natural Killer Cell Receptor Clone Cl-6
P58 Nk Receptor Cl-6
P58.2 Mhc Class-I-Specific Nk Receptor
Cd Antigen Cd158b2
Database Links Reactome: R-HSA-198933
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Alternative Antibody Names Anti-Killer Cell Immunoglobulin-Like Receptor 2dl3 antibody
Anti-Cd158 Antigen-Like Family Member B2 antibody
Anti-Kir-023gb antibody
Anti-Killer Inhibitory Receptor Cl 2-3 antibody
Anti-Nkat2a antibody
Anti-Nkat2b antibody
Anti-Natural Killer-Associated Transcript 2 antibody
Anti-Nkat-2 antibody
Anti-P58 Natural Killer Cell Receptor Clone Cl-6 antibody
Anti-P58 Nk Receptor Cl-6 antibody
Anti-P58.2 Mhc Class-I-Specific Nk Receptor antibody
Anti-Cd Antigen Cd158b2 antibody
Anti-KIR2DL3 antibody
Anti-CD158B2 antibody
Anti-KIRCL23 antibody
Anti-NKAT2 antibody

Information sourced from Uniprot.org