Anti-KIR2DL3 antibody (22-245) (STJ24316)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal KIR2DL3 (22-245) antibody for use in WB, IF, ICC and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | KIR2DL3 |
| Gene ID | 3804 |
| Uniprot ID | KI2L3_HUMAN |
| Immunogen Region | 22-245 |
| Immunogen Sequence | HEGVHRKPSLLAHPGPLVKS EETVILQCWSDVRFQHFLLH REGKFKDTLHLIGEHHDGVS KANFSIGPMMQDLAGTYRCY GSVTHSPYQLSAPSDPLDIV ITGLYEKPSLSAQPGPTVLA GESVTLSCSSRSSYDMYHLS REGEAHERRFSAGPKVNGTF QADFPLGPATHGGTYRCFGS FRDSPYEWSNSSDPLLVSVT GNPSNSWPSPTEPSSETGNP RHLH |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 22-245 of human KIR2DL3 (NP_056952.2). |
Additional Info
| Function | Receptor on natural killer (NK) cells for HLA-C alleles (HLA-Cw1, HLA-Cw3 and HLA-Cw7). Inhibits the activity of NK cells thus preventing cell lysis. |
| Protein Name | Killer Cell Immunoglobulin-Like Receptor 2dl3Cd158 Antigen-Like Family Member B2Kir-023gbKiller Inhibitory Receptor Cl 2-3Nkat2aNkat2bNatural Killer-Associated Transcript 2Nkat-2P58 Natural Killer Cell Receptor Clone Cl-6P58 Nk Receptor Cl-6P58.2 Mhc Class-I-Specific Nk ReceptorCd Antigen Cd158b2 |
| Database Links | Reactome: R-HSA-198933 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Killer Cell Immunoglobulin-Like Receptor 2dl3 antibodyAnti-Cd158 Antigen-Like Family Member B2 antibodyAnti-Kir-023gb antibodyAnti-Killer Inhibitory Receptor Cl 2-3 antibodyAnti-Nkat2a antibodyAnti-Nkat2b antibodyAnti-Natural Killer-Associated Transcript 2 antibodyAnti-Nkat-2 antibodyAnti-P58 Natural Killer Cell Receptor Clone Cl-6 antibodyAnti-P58 Nk Receptor Cl-6 antibodyAnti-P58.2 Mhc Class-I-Specific Nk Receptor antibodyAnti-Cd Antigen Cd158b2 antibodyAnti-KIR2DL3 antibodyAnti-CD158B2 antibodyAnti-KIRCL23 antibodyAnti-NKAT2 antibody |
Information sourced from Uniprot.org