| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Jupiter microtubule associated homolog 1 is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
JPT1 |
| Gene ID: |
51155 |
| Uniprot ID: |
JUPI1_HUMAN |
| Specificity: |
This antibody detects endogenous levels of HN1 at Human, Mouse, Rat |
| Immunogen: |
Synthesized peptide derived from human HN1 |
| Function | Modulates negatively AKT-mediated GSK3B signaling. Induces CTNNB1 'Ser-33' phosphorylation and degradation through the suppression of the inhibitory 'Ser-9' phosphorylation of GSK3B, which represses the function of the APC:CTNNB1:GSK3B complex and the interaction with CDH1/E-cadherin in adherent junctions. Plays a role in the regulation of cell cycle and cell adhesion. Has an inhibitory role on AR-signaling pathway through the induction of receptor proteasomal degradation. |
| Protein Name | Jupiter Microtubule Associated Homolog 1Androgen-Regulated Protein 2Hematological And Neurological Expressed 1 Protein Cleaved Into - Jupiter Microtubule Associated Homolog 1 - N-Terminally Processed |
| Cellular Localisation | NucleusCytoplasm |
| Alternative Antibody Names | Anti-Jupiter Microtubule Associated Homolog 1 antibodyAnti-Androgen-Regulated Protein 2 antibodyAnti-Hematological And Neurological Expressed 1 Protein Cleaved Into - Jupiter Microtubule Associated Homolog 1 - N-Terminally Processed antibodyAnti-JPT1 antibodyAnti-ARM2 antibodyAnti-HN1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
