| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Jupiter microtubule associated homolog 1 is suitable for use in Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | JPT1 |
| Gene ID: | 51155 |
| Uniprot ID: | JUPI1_HUMAN |
| Specificity: | This antibody detects endogenous levels of HN1 at Human, Mouse, Rat |
| Immunogen: | Synthesized peptide derived from human HN1 |
| Function | Modulates negatively AKT-mediated GSK3B signaling. Induces CTNNB1 'Ser-33' phosphorylation and degradation through the suppression of the inhibitory 'Ser-9' phosphorylation of GSK3B, which represses the function of the APC:CTNNB1:GSK3B complex and the interaction with CDH1/E-cadherin in adherent junctions. Plays a role in the regulation of cell cycle and cell adhesion. Has an inhibitory role on AR-signaling pathway through the induction of receptor proteasomal degradation. |
| Protein Name | Jupiter Microtubule Associated Homolog 1 Androgen-Regulated Protein 2 Hematological And Neurological Expressed 1 Protein Cleaved Into - Jupiter Microtubule Associated Homolog 1 - N-Terminally Processed |
| Cellular Localisation | Nucleus Cytoplasm |
| Alternative Antibody Names | Anti-Jupiter Microtubule Associated Homolog 1 antibody Anti-Androgen-Regulated Protein 2 antibody Anti-Hematological And Neurological Expressed 1 Protein Cleaved Into - Jupiter Microtubule Associated Homolog 1 - N-Terminally Processed antibody Anti-JPT1 antibody Anti-ARM2 antibody Anti-HN1 antibody |
Information sourced from Uniprot.org