Host: |
Rabbit |
Applications: |
WB/IHC/IF/ELISA |
Reactivity: |
Human/Rat/Mouse |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-Interleukin-5 receptor subunit alpha (41-90 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: |
1 mg/mL |
Dilution Range: |
WB 1:500-1:2000IHC-P 1:100-300ELISA 1:20000IF 1:50-200 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
IL5RA |
Gene ID: |
3568 |
Uniprot ID: |
IL5RA_HUMAN |
Immunogen Region: |
41-90 aa |
Specificity: |
IL-5R Alpha Polyclonal Antibody detects endogenous levels of IL-5R Alpha protein. |
Immunogen: |
The antiserum was produced against synthesized peptide derived from the N-terminal region of human IL5RA at the amino acid range 41-90 |
Function | Cell surface receptor that plays an important role in the survival, differentiation, and chemotaxis of eosinophils. Acts by forming an heterodimeric receptor with CSF2RB subunit and subsequently binding to interleukin-5. In unstimulated conditions, interacts constitutively with JAK2. Heterodimeric receptor activation leads to JAK2 stimulation and subsequent activation of the JAK-STAT pathway. |
Protein Name | Interleukin-5 Receptor Subunit AlphaIl-5 Receptor Subunit AlphaIl-5r Subunit AlphaIl-5r-AlphaIl-5raCdw125Cd Antigen Cd125 |
Database Links | Reactome: R-HSA-512988Reactome: R-HSA-5673001Reactome: R-HSA-912526 |
Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
Alternative Antibody Names | Anti-Interleukin-5 Receptor Subunit Alpha antibodyAnti-Il-5 Receptor Subunit Alpha antibodyAnti-Il-5r Subunit Alpha antibodyAnti-Il-5r-Alpha antibodyAnti-Il-5ra antibodyAnti-Cdw125 antibodyAnti-Cd Antigen Cd125 antibodyAnti-IL5RA antibodyAnti-IL5R antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance