• Western blot analysis of lysate from K562 cells, using IL5RA Antibody.
  • Western blot analysis of K562 cells using IL-5R Alpha Polyclonal Antibody.. Secondary antibody was diluted at 1:20000

Anti-IL5RA antibody (41-90 aa) (STJ96579)

SKU:
STJ96579

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Interleukin-5 receptor subunit alpha (41-90 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC-P 1:100-300
ELISA 1:20000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: IL5RA
Gene ID: 3568
Uniprot ID: IL5RA_HUMAN
Immunogen Region: 41-90 aa
Specificity: IL-5R Alpha Polyclonal Antibody detects endogenous levels of IL-5R Alpha protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the N-terminal region of human IL5RA at the amino acid range 41-90
Function Cell surface receptor that plays an important role in the survival, differentiation, and chemotaxis of eosinophils. Acts by forming an heterodimeric receptor with CSF2RB subunit and subsequently binding to interleukin-5. In unstimulated conditions, interacts constitutively with JAK2. Heterodimeric receptor activation leads to JAK2 stimulation and subsequent activation of the JAK-STAT pathway.
Protein Name Interleukin-5 Receptor Subunit Alpha
Il-5 Receptor Subunit Alpha
Il-5r Subunit Alpha
Il-5r-Alpha
Il-5ra
Cdw125
Cd Antigen Cd125
Database Links Reactome: R-HSA-512988
Reactome: R-HSA-5673001
Reactome: R-HSA-912526
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Alternative Antibody Names Anti-Interleukin-5 Receptor Subunit Alpha antibody
Anti-Il-5 Receptor Subunit Alpha antibody
Anti-Il-5r Subunit Alpha antibody
Anti-Il-5r-Alpha antibody
Anti-Il-5ra antibody
Anti-Cdw125 antibody
Anti-Cd Antigen Cd125 antibody
Anti-IL5RA antibody
Anti-IL5R antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance