Anti-IL5RA antibody (41-90 aa) (STJ96579)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the N-terminal region of human IL5RA at the amino acid range 41-90
General Information
| Short Description | Rabbit polyclonal anti-Interleukin-5 receptor subunit alpha (41-90 aa) for use in WB, IHC, IF and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000IHC-P 1:100-300ELISA 1:20000IF 1:50-200 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | IL5RA |
| Gene ID | 3568 |
| Uniprot ID | IL5RA_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the N-terminal region of human IL5RA at the amino acid range 41-90 |
| Immunogen Region | 41-90 aa |
| Specificity | IL-5R Alpha Polyclonal Antibody detects endogenous levels of IL-5R Alpha protein. |
Additional Info
| Function | Cell surface receptor that plays an important role in the survival, differentiation, and chemotaxis of eosinophils. Acts by forming a heterodimeric receptor with CSF2RB subunit and subsequently binding to interleukin-5. In unstimulated conditions, interacts constitutively with JAK2. Heterodimeric receptor activation leads to JAK2 stimulation and subsequent activation of the JAK-STAT pathway. |
| Protein Name | Interleukin-5 Receptor Subunit AlphaIl-5 Receptor Subunit AlphaIl-5r Subunit AlphaIl-5r-AlphaIl-5raCdw125Cd Antigen Cd125 |
| Database Links | Reactome: R-HSA-512988Reactome: R-HSA-5673001Reactome: R-HSA-912526 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Interleukin-5 Receptor Subunit Alpha antibodyAnti-Il-5 Receptor Subunit Alpha antibodyAnti-Il-5r Subunit Alpha antibodyAnti-Il-5r-Alpha antibodyAnti-Il-5ra antibodyAnti-Cdw125 antibodyAnti-Cd Antigen Cd125 antibodyAnti-IL5RA antibodyAnti-IL5R antibody |
Information sourced from Uniprot.org