Anti-HPRT1 antibody (1-218) (STJ11104570)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal Hypoxanthine-Guanine Phosphoribosyltransferase (1-218) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:100-1:500ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | HPRT1 |
| Gene ID | 3251 |
| Uniprot ID | HPRT_HUMAN |
| Immunogen Region | 1-218 |
| Immunogen Sequence | MATRSPGVVISDDEPGYDLD LFCIPNHYAEDLERVFIPHG LIMDRTERLARDVMKEMGGH HIVALCVLKGGYKFFADLLD YIKALNRNSDRSIPMTVDFI RLKSYCNDQSTGDIKVIGGD DLSTLTGKNVLIVEDIIDTG KTMQTLLSLVRQYNPKMVKV ASLLVKRTPRSVGYKPDFVG FEIPDKFVVGYALDYNEYFR DLNHVCVISETGKAKYKA |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-218 of human HPRT1 (NP_000185.1). |
Additional Info
| Function | Converts guanine to guanosine monophosphate, and hypoxanthine to inosine monophosphate. Transfers the 5-phosphoribosyl group from 5-phosphoribosylpyrophosphate onto the purine. Plays a central role in the generation of purine nucleotides through the purine salvage pathway. |
| Protein Name | Hypoxanthine-Guanine PhosphoribosyltransferaseHgprtHgprtase |
| Database Links | Reactome: R-HSA-74217Reactome: R-HSA-9734281Reactome: R-HSA-9748787 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Hypoxanthine-Guanine Phosphoribosyltransferase antibodyAnti-Hgprt antibodyAnti-Hgprtase antibodyAnti-HPRT1 antibodyAnti-HPRT antibody |
Information sourced from Uniprot.org