| Short Description : | Rabbit polyclonal Hypoxanthine-Guanine Phosphoribosyltransferase (1-218) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:100-1:500ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | HPRT1 |
| Gene ID: | 3251 |
| Uniprot ID: | HPRT_HUMAN |
| Immunogen Region: | 1-218 |
| Immunogen Sequence: | MATRSPGVVISDDEPGYDLD LFCIPNHYAEDLERVFIPHG LIMDRTERLARDVMKEMGGH HIVALCVLKGGYKFFADLLD YIKALNRNSDRSIPMTVDFI RLKSYCNDQSTGDIKVIGGD DLSTLTGKNVLIVEDIIDTG KTMQTLLSLVRQYNPKMVKV ASLLVKRTPRSVGYKPDFVG FEIPDKFVVGYALDYNEYFR DLNHVCVISETGKAKYKA |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-218 of human HPRT1 (NP_000185.1). |
| Function | Converts guanine to guanosine monophosphate, and hypoxanthine to inosine monophosphate. Transfers the 5-phosphoribosyl group from 5-phosphoribosylpyrophosphate onto the purine. Plays a central role in the generation of purine nucleotides through the purine salvage pathway. |
| Protein Name | Hypoxanthine-Guanine PhosphoribosyltransferaseHgprtHgprtase |
| Database Links | Reactome: R-HSA-74217Reactome: R-HSA-9734281Reactome: R-HSA-9748787 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Hypoxanthine-Guanine Phosphoribosyltransferase antibodyAnti-Hgprt antibodyAnti-Hgprtase antibodyAnti-HPRT1 antibodyAnti-HPRT antibody |
Information sourced from Uniprot.org
