| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-GPR62 (150-250) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:1000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
GPR62 |
| Gene ID: |
118442 |
| Uniprot ID: |
GPR62_HUMAN |
| Immunogen Region: |
150-250 |
| Immunogen: |
A synthetic peptide corresponding to a sequence within amino acids 150-250 of human GPR62 (NP_543141.3). |
| Immunogen Sequence: |
GTPPAPPPAPARCSVLAGGL GPFRPLWALLAFALPALLLL GAYGGIFVVARRAALRPPRP ARGSRLHSDSLDSRLSILPP LRPRLPGGKAALAPALAVGQ F |
| Tissue Specificity | Expressed in brain.detected in the basal forebrain, frontal cortex, caudate, putamen, thalamus and hippocampus. |
| Function | Orphan G-protein coupled receptor. Constitutively activates the G(q/11)/inositol phosphate and the G(s)-alpha/cAMP signaling pathways. Has spontaneous activity for beta-arrestin recruitment. Shows a reciprocal modulation of signaling functions with the melatonin receptor MTNR1B most likely through receptor heteromerization. |
| Protein Name | G-Protein Coupled Receptor 62G-Protein Coupled Receptor Gpcr8Hgpcr8G-Protein Coupled Receptor Kpg_005 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinEndosome MembraneColocalizes With Arrb2 In The Endosome |
| Alternative Antibody Names | Anti-G-Protein Coupled Receptor 62 antibodyAnti-G-Protein Coupled Receptor Gpcr8 antibodyAnti-Hgpcr8 antibodyAnti-G-Protein Coupled Receptor Kpg_005 antibodyAnti-GPR62 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
