Anti-GPR62 antibody (150-250) (STJ118603)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal GPR62 (150-250) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | GPR62 |
| Gene ID | 118442 |
| Uniprot ID | GPR62_HUMAN |
| Immunogen Region | 150-250 |
| Immunogen Sequence | GTPPAPPPAPARCSVLAGGL GPFRPLWALLAFALPALLLL GAYGGIFVVARRAALRPPRP ARGSRLHSDSLDSRLSILPP LRPRLPGGKAALAPALAVGQ F |
| Specificity | A synthetic peptide corresponding to a sequence within amino acids 150-250 of human GPR62 (NP_543141.3). |
Additional Info
| Tissue Specificity | Expressed in brain.detected in the basal forebrain, frontal cortex, caudate, putamen, thalamus and hippocampus. |
| Function | Orphan G-protein coupled receptor. Constitutively activates the G(q/11)/inositol phosphate and the G(s)-alpha/cAMP signaling pathways. Has spontaneous activity for beta-arrestin recruitment. Shows a reciprocal modulation of signaling functions with the melatonin receptor MTNR1B most likely through receptor heteromerization. |
| Protein Name | G-Protein Coupled Receptor 62G-Protein Coupled Receptor Gpcr8Hgpcr8G-Protein Coupled Receptor Kpg_005 |
| Database Links | |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinEndosome MembraneColocalizes With Arrb2 In The Endosome |
| Alternative Antibody Names | Anti-G-Protein Coupled Receptor 62 antibodyAnti-G-Protein Coupled Receptor Gpcr8 antibodyAnti-Hgpcr8 antibodyAnti-G-Protein Coupled Receptor Kpg_005 antibodyAnti-GPR62 antibody |
Information sourced from Uniprot.org