Anti-FAM120A antibody (1-140) (STJ119711)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal FAM120A (1-140) antibody for use in WB and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | FAM120A |
| Gene ID | 23196 |
| Uniprot ID | F120A_HUMAN |
| Immunogen Region | 1-140 |
| Immunogen Sequence | MGVQGFQDYIEKHCPSAVVP VELQKLARGSLVGGGRQRPP QTPLRLLVDADNCLHRLYGG FYTDWVSGGQWNHMLGYLAA LAKACFGGNIELFVFFNGAL EKARLHEWVKRQGNERQTAQ QIVSHVQNKGTPPPKVWFLP |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-140 of human FAM120A (NP_055427.2). |
Additional Info
| Tissue Specificity | Widely expressed. In gastric mucosa, detected in the bottom region of the foveolar epithelium (at protein level). |
| Post Translational Modifications | Arg-982 is dimethylated, probably to asymmetric dimethylarginine. Phosphorylated on tyrosine by SRC family protein kinases upon oxidative stress, for instance following UV irradiation. |
| Function | Component of the oxidative stress-induced survival signaling. May regulate the activation of SRC family protein kinases. May act as a scaffolding protein enabling SRC family protein kinases to phosphorylate and activate PI3-kinase. Binds IGF2 RNA and promotes the production of IGF2 protein. |
| Protein Name | Constitutive Coactivator Of Ppar-Gamma-Like Protein 1Oxidative Stress-Associated Src ActivatorProtein Fam120a |
| Database Links | |
| Cellular Localisation | CytoplasmCell MembranePeripheral Membrane ProteinCytoplasmic SideTranslocates From The Cytosol To Plasma Membrane After Uv Irradiation |
| Alternative Antibody Names | Anti-Constitutive Coactivator Of Ppar-Gamma-Like Protein 1 antibodyAnti-Oxidative Stress-Associated Src Activator antibodyAnti-Protein Fam120a antibodyAnti-FAM120A antibodyAnti-C9orf10 antibodyAnti-KIAA0183 antibodyAnti-OSSA antibody |
Information sourced from Uniprot.org