Anti-FAM120A antibody (1-140) (STJ119711)

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STJ119711
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Host: Rabbit
Applications: WB/ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:2000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: FAM120A
Gene ID: 23196
Uniprot ID: F120A_HUMAN
Immunogen Region: 1-140
Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 1-140 of human FAM120A (NP_055427.2).
Immunogen Sequence: MGVQGFQDYIEKHCPSAVVP VELQKLARGSLVGGGRQRPP QTPLRLLVDADNCLHRLYGG FYTDWVSGGQWNHMLGYLAA LAKACFGGNIELFVFFNGAL EKARLHEWVKRQGNERQTAQ QIVSHVQNKGTPPPKVWFLP
Tissue Specificity Widely expressed. In gastric mucosa, detected in the bottom region of the foveolar epithelium (at protein level).
Post Translational Modifications Arg-982 is dimethylated, probably to asymmetric dimethylarginine. Phosphorylated on tyrosine by SRC family protein kinases upon oxidative stress, for instance following UV irradiation.
Function Component of the oxidative stress-induced survival signaling. May regulate the activation of SRC family protein kinases. May act as a scaffolding protein enabling SRC family protein kinases to phosphorylate and activate PI3-kinase. Binds IGF2 RNA and promotes the production of IGF2 protein.
Protein Name Constitutive Coactivator Of Ppar-Gamma-Like Protein 1
Oxidative Stress-Associated Src Activator
Protein Fam120a
Database Links
Cellular Localisation Cytoplasm
Cell Membrane
Peripheral Membrane Protein
Cytoplasmic Side
Translocates From The Cytosol To Plasma Membrane After Uv Irradiation
Alternative Antibody Names Anti-Constitutive Coactivator Of Ppar-Gamma-Like Protein 1 antibody
Anti-Oxidative Stress-Associated Src Activator antibody
Anti-Protein Fam120a antibody
Anti-FAM120A antibody
Anti-C9orf10 antibody
Anti-KIAA0183 antibody
Anti-OSSA antibody

Information sourced from Uniprot.org