| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-FAM120A (1-140) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
FAM120A |
| Gene ID: |
23196 |
| Uniprot ID: |
F120A_HUMAN |
| Immunogen Region: |
1-140 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-140 of human FAM120A (NP_055427.2). |
| Immunogen Sequence: |
MGVQGFQDYIEKHCPSAVVP VELQKLARGSLVGGGRQRPP QTPLRLLVDADNCLHRLYGG FYTDWVSGGQWNHMLGYLAA LAKACFGGNIELFVFFNGAL EKARLHEWVKRQGNERQTAQ QIVSHVQNKGTPPPKVWFLP |
| Tissue Specificity | Widely expressed. In gastric mucosa, detected in the bottom region of the foveolar epithelium (at protein level). |
| Post Translational Modifications | Arg-982 is dimethylated, probably to asymmetric dimethylarginine. Phosphorylated on tyrosine by SRC family protein kinases upon oxidative stress, for instance following UV irradiation. |
| Function | Component of the oxidative stress-induced survival signaling. May regulate the activation of SRC family protein kinases. May act as a scaffolding protein enabling SRC family protein kinases to phosphorylate and activate PI3-kinase. Binds IGF2 RNA and promotes the production of IGF2 protein. |
| Protein Name | Constitutive Coactivator Of Ppar-Gamma-Like Protein 1Oxidative Stress-Associated Src ActivatorProtein Fam120a |
| Cellular Localisation | CytoplasmCell MembranePeripheral Membrane ProteinCytoplasmic SideTranslocates From The Cytosol To Plasma Membrane After Uv Irradiation |
| Alternative Antibody Names | Anti-Constitutive Coactivator Of Ppar-Gamma-Like Protein 1 antibodyAnti-Oxidative Stress-Associated Src Activator antibodyAnti-Protein Fam120a antibodyAnti-FAM120A antibodyAnti-C9orf10 antibodyAnti-KIAA0183 antibodyAnti-OSSA antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
