| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Dr1-associated corepressor is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
DRAP1 |
| Gene ID: |
10589 |
| Uniprot ID: |
NC2A_HUMAN |
| Specificity: |
This antibody detects endogenous levels of DRAP1 at Human, Mouse, Rat |
| Immunogen: |
Synthesized peptide derived from human DRAP1 |
| Post Translational Modifications | Phosphorylation reduces DNA binding, but has no effect on heterodimerization and TBP binding. |
| Function | The association of the DR1/DRAP1 heterodimer with TBP results in a functional repression of both activated and basal transcription of class II genes. This interaction precludes the formation of a transcription-competent complex by inhibiting the association of TFIIA and/or TFIIB with TBP. Can bind to DNA on its own. |
| Protein Name | Dr1-Associated CorepressorDr1-Associated Protein 1Negative Cofactor 2-AlphaNc2-Alpha |
| Database Links | Reactome: R-HSA-1181150Reactome: R-HSA-1502540 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Dr1-Associated Corepressor antibodyAnti-Dr1-Associated Protein 1 antibodyAnti-Negative Cofactor 2-Alpha antibodyAnti-Nc2-Alpha antibodyAnti-DRAP1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
