Anti-DRAP1 antibody (STJA0009194)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human DRAP1
General Information
| Short Description | Rabbit polyclonal anti-Dr1-associated corepressor for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | DRAP1 |
| Gene ID | 10589 |
| Uniprot ID | NC2A_HUMAN |
| Immunogen | Synthesized peptide derived from human DRAP1 |
| Specificity | This antibody detects endogenous levels of DRAP1 at Human, Mouse, Rat |
Additional Info
| Post Translational Modifications | Phosphorylation reduces DNA binding, but has no effect on heterodimerization and TBP binding. |
| Function | The association of the DR1/DRAP1 heterodimer with TBP results in a functional repression of both activated and basal transcription of class II genes. This interaction precludes the formation of a transcription-competent complex by inhibiting the association of TFIIA and/or TFIIB with TBP. Can bind to DNA on its own. |
| Protein Name | Dr1-Associated CorepressorDr1-Associated Protein 1Negative Cofactor 2-AlphaNc2-Alpha |
| Database Links | Reactome: R-HSA-1181150Reactome: R-HSA-1502540 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Dr1-Associated Corepressor antibodyAnti-Dr1-Associated Protein 1 antibodyAnti-Negative Cofactor 2-Alpha antibodyAnti-Nc2-Alpha antibodyAnti-DRAP1 antibody |
Information sourced from Uniprot.org