| Short Description : | Rabbit polyclonal anti-Dr1-associated corepressor for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range: | WB 1:500-2000 |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | DRAP1 |
| Gene ID: | 10589 |
| Uniprot ID: | NC2A_HUMAN |
| Immunogen: | Synthesized peptide derived from human DRAP1 |
| Specificity: | This antibody detects endogenous levels of DRAP1 at Human, Mouse, Rat |
| Post Translational Modifications | Phosphorylation reduces DNA binding, but has no effect on heterodimerization and TBP binding. |
| Function | The association of the DR1/DRAP1 heterodimer with TBP results in a functional repression of both activated and basal transcription of class II genes. This interaction precludes the formation of a transcription-competent complex by inhibiting the association of TFIIA and/or TFIIB with TBP. Can bind to DNA on its own. |
| Protein Name | Dr1-Associated CorepressorDr1-Associated Protein 1Negative Cofactor 2-AlphaNc2-Alpha |
| Database Links | Reactome: R-HSA-1181150Reactome: R-HSA-1502540 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Dr1-Associated Corepressor antibodyAnti-Dr1-Associated Protein 1 antibodyAnti-Negative Cofactor 2-Alpha antibodyAnti-Nc2-Alpha antibodyAnti-DRAP1 antibody |
Information sourced from Uniprot.org
