Anti-DHCR24 antibody (STJA0006968)

SKU:
STJA0006968
€60.00 - €315.00
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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit polyclonal antibody anti-Delta24-sterol reductase is suitable for use in Western Blot research applications.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: DHCR24
Gene ID: 1718
Uniprot ID: DHC24_HUMAN
Specificity: This antibody detects endogenous levels of DHCR24 at Human, Mouse, Rat
Immunogen: Synthesized peptide derived from human DHCR24
Function Catalyzes the reduction of the delta-24 double bond of sterol intermediates during cholesterol biosynthesis. In addition to its cholesterol-synthesizing activity, can protect cells from oxidative stress by reducing caspase 3 activity during apoptosis induced by oxidative stress. Also protects against amyloid-beta peptide-induced apoptosis.
Protein Name Delta(24-Sterol Reductase
24-Dehydrocholesterol Reductase
3-Beta-Hydroxysterol Delta-24-Reductase
Diminuto/Dwarf1 Homolog
Seladin-1
Database Links Reactome: R-HSA-191273
Reactome: R-HSA-6807047
Reactome: R-HSA-6807062
Cellular Localisation Endoplasmic Reticulum Membrane
Single-Pass Membrane Protein
Golgi Apparatus Membrane
Alternative Antibody Names Anti-Delta(24-Sterol Reductase antibody
Anti-24-Dehydrocholesterol Reductase antibody
Anti-3-Beta-Hydroxysterol Delta-24-Reductase antibody
Anti-Diminuto/Dwarf1 Homolog antibody
Anti-Seladin-1 antibody
Anti-DHCR24 antibody
Anti-KIAA0018 antibody

Information sourced from Uniprot.org

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