| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Delta24-sterol reductase is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
DHCR24 |
| Gene ID: |
1718 |
| Uniprot ID: |
DHC24_HUMAN |
| Specificity: |
This antibody detects endogenous levels of DHCR24 at Human, Mouse, Rat |
| Immunogen: |
Synthesized peptide derived from human DHCR24 |
| Function | Catalyzes the reduction of the delta-24 double bond of sterol intermediates during cholesterol biosynthesis. In addition to its cholesterol-synthesizing activity, can protect cells from oxidative stress by reducing caspase 3 activity during apoptosis induced by oxidative stress. Also protects against amyloid-beta peptide-induced apoptosis. |
| Protein Name | Delta(24-Sterol Reductase24-Dehydrocholesterol Reductase3-Beta-Hydroxysterol Delta-24-ReductaseDiminuto/Dwarf1 HomologSeladin-1 |
| Database Links | Reactome: R-HSA-191273Reactome: R-HSA-6807047Reactome: R-HSA-6807062 |
| Cellular Localisation | Endoplasmic Reticulum MembraneSingle-Pass Membrane ProteinGolgi Apparatus Membrane |
| Alternative Antibody Names | Anti-Delta(24-Sterol Reductase antibodyAnti-24-Dehydrocholesterol Reductase antibodyAnti-3-Beta-Hydroxysterol Delta-24-Reductase antibodyAnti-Diminuto/Dwarf1 Homolog antibodyAnti-Seladin-1 antibodyAnti-DHCR24 antibodyAnti-KIAA0018 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
