Anti-DFFB antibody (109-338) (STJ112149)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal DFFB (109-338) antibody for use in WB, IHC-P and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:200-1:1000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | DFFB |
| Gene ID | 1677 |
| Uniprot ID | DFFB_HUMAN |
| Immunogen Region | 109-338 |
| Immunogen Sequence | DEQAPQRQRLLADLLHNVSQ NIAAETRAEDPPWFEGLESR FQSKSGYLRYSCESRIRSYL REVSSYPSTVGAEAQEEFLR VLGSMCQRLRSMQYNGSYFD RGAKGGSRLCTPEGWFSCQG PFDMDSCLSRHSINPYSNRE SRILFSTWNLDHIIEKKRTI IPTLVEAIKEQDGREVDWEY FYGLLFTSENLKLVHIVCHK KTTHKLNCDPSRIYKPQTRL KRKQPVRKRQ |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 109-338 of human DFFB (NP_004393.1). |
Additional Info
| Function | Nuclease that induces DNA fragmentation and chromatin condensation during apoptosis. Degrades naked DNA and induces apoptotic morphology. |
| Protein Name | Dna Fragmentation Factor Subunit BetaCaspase-Activated DeoxyribonucleaseCadCaspase-Activated DnaseCaspase-Activated NucleaseCpanDna Fragmentation Factor 40 Kda SubunitDff-40 |
| Database Links | Reactome: R-HSA-140342 |
| Cellular Localisation | CytoplasmNucleus |
| Alternative Antibody Names | Anti-Dna Fragmentation Factor Subunit Beta antibodyAnti-Caspase-Activated Deoxyribonuclease antibodyAnti-Cad antibodyAnti-Caspase-Activated Dnase antibodyAnti-Caspase-Activated Nuclease antibodyAnti-Cpan antibodyAnti-Dna Fragmentation Factor 40 Kda Subunit antibodyAnti-Dff-40 antibodyAnti-DFFB antibodyAnti-CAD antibodyAnti-DFF2 antibodyAnti-DFF40 antibody |
Information sourced from Uniprot.org