| Host: |
Goat |
| Applications: |
Pep-ELISA/WB/IHC |
| Reactivity: |
Human/Mouse/Rat/Dog |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Goat polyclonal antibody anti-DEAD-box protein 6 (C-Term) is suitable for use in ELISA, Western Blot and Immunohistochemistry research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: |
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: |
0.5 mg/mL |
| Dilution Range: |
WB-0.3-1µg/mlIHC-5µg/mlELISA-antibody detection limit dilution 1:128000. |
| Storage Instruction: |
Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: |
DDX6 |
| Gene ID: |
1656 |
| Uniprot ID: |
DDX6_HUMAN |
| Immunogen Region: |
C-Term |
| Accession Number: |
NP_004388.1 |
| Immunogen Sequence: |
AEYHSEPVEDEKP |
| Post Translational Modifications | Sumoylated. |
| Function | Essential for the formation of P-bodies, cytosolic membrane-less ribonucleoprotein granules involved in RNA metabolism through the coordinated storage of mRNAs encoding regulatory functions. Plays a role in P-bodies to coordinate the storage of translationally inactive mRNAs in the cytoplasm and prevent their degradation. In the process of mRNA degradation, plays a role in mRNA decapping. Blocks autophagy in nutrient-rich conditions by repressing the expression of ATG-related genes through degradation of their transcripts. |
| Protein Name | Probable Atp-Dependent Rna Helicase Ddx6Atp-Dependent Rna Helicase P54Dead Box Protein 6Oncogene Rck |
| Database Links | Reactome: R-HSA-430039 |
| Cellular Localisation | CytoplasmP-BodyNucleusImported In The Nucleus Via Interaction With Eif4enif1/4e-T Via A Piggy-Back MechanismUpon Cellular StressRelocalizes To Stress Granules |
| Alternative Antibody Names | Anti-Probable Atp-Dependent Rna Helicase Ddx6 antibodyAnti-Atp-Dependent Rna Helicase P54 antibodyAnti-Dead Box Protein 6 antibodyAnti-Oncogene Rck antibodyAnti-DDX6 antibodyAnti-HLR2 antibodyAnti-RCK antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
