Anti-CYRIB antibody (STJA0007514)

SKU:
STJA0007514
€58.80 - €313.20
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Short Description :Rabbit polyclonal anti-CYFIP-related Rac1 interactor B for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents.
Applications:WB
Host:Rabbit
Reactivity:Human/Mouse
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Polyclonal
Isotype:IgG
Conjugation:Unconjugated
Concentration:1 mg/mL
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Dilution Range:WB 1:500-2000
Formulation:Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage Instruction:Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol:CYRIB
Gene ID:51571
Uniprot ID:CYRIB_HUMAN
Immunogen:Synthesized peptide derived from human FAM49B
Specificity:This antibody detects endogenous levels of FAM49B at Human, Mouse
Function Negatively regulates RAC1 signaling and RAC1-driven cytoskeletal remodeling. Regulates chemotaxis, cell migration and epithelial polarization by controlling the polarity, plasticity, duration and extent of protrusions. Limits Rac1 mediated activation of the Scar/WAVE complex, focuses protrusion signals and regulates pseudopod complexity by inhibiting Scar/WAVE-induced actin polymerization. Protects against Salmonella bacterial infection. Attenuates processes such as macropinocytosis, phagocytosis and cell migration and restrict sopE-mediated bacterial entry. Also restricts infection mediated by Mycobacterium tuberculosis and Listeria monocytogenes. Involved in the regulation of mitochondrial dynamics and oxidative stress.
Protein Name Cyfip-Related Rac1 Interactor B
L1
Database Links Reactome: R-HSA-114608
Cellular Localisation Membrane
Lipid-Anchor
Mitochondrion
Alternative Antibody Names Anti-Cyfip-Related Rac1 Interactor B antibody
Anti-L1 antibody
Anti-CYRIB antibody
Anti-CYRI antibody
Anti-FAM49B antibody
Anti-BM-009 antibody

Information sourced from Uniprot.org

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