Anti-COPZ1 antibody (1-177) (STJ114041)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal COPZ1 (1-177) antibody for use in WB, IF, ICC and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | COPZ1 |
| Gene ID | 22818 |
| Uniprot ID | COPZ1_HUMAN |
| Immunogen Region | 1-177 |
| Immunogen Sequence | MEALILEPSLYTVKAILILD NDGDRLFAKYYDDTYPSVKE QKAFEKNIFNKTHRTDSEIA LLEGLTVVYKSSIDLYFYVI GSSYENELMLMAVLNCLFDS LSQMLRKNVEKRALLENMEG LFLAVDEIVDGGVILESDPQ QVVHRVALRGEDVPLTEQTV SQVLQSAKEQIKWSLLR |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-177 of human COPZ1 (NP_057141.1). |
Additional Info
| Function | The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex. |
| Protein Name | Coatomer Subunit Zeta-1Zeta-1-Coat ProteinZeta-1 Cop |
| Database Links | Reactome: R-HSA-6807878Reactome: R-HSA-6811434 |
| Cellular Localisation | CytoplasmGolgi Apparatus MembranePeripheral Membrane ProteinCytoplasmic SideCytoplasmic VesicleCopi-Coated Vesicle MembraneThe Coatomer Is Cytoplasmic Or Polymerized On The Cytoplasmic Side Of The GolgiAs Well As On The Vesicles/Buds Originating From It |
| Alternative Antibody Names | Anti-Coatomer Subunit Zeta-1 antibodyAnti-Zeta-1-Coat Protein antibodyAnti-Zeta-1 Cop antibodyAnti-COPZ1 antibodyAnti-COPZ antibodyAnti-CGI-120 antibodyAnti-HSPC181 antibody |
Information sourced from Uniprot.org