Anti-CMTM4 antibody (161-210 aa) (STJ92351)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human CKLF4 at the amino acid range 161-210
General Information
| Short Description | Rabbit polyclonal anti-CKLF-like MARVEL transmembrane domain-containing protein 4 (161-210 aa) for use in WB, IHC, IF and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000IHC-P 1:100-300ELISA 1:20000IF 1:100-300 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CMTM4 |
| Gene ID | 146223 |
| Uniprot ID | CKLF4_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human CKLF4 at the amino acid range 161-210 |
| Immunogen Region | 161-210 aa |
| Specificity | CMTM4 Polyclonal Antibody detects endogenous levels of CMTM4 protein. |
Additional Info
| Function | Acts as a backup for CMTM6 to regulate plasma membrane expression of PD-L1/CD274, an immune inhibitory ligand critical for immune tolerance to self and antitumor immunity. May protect PD-L1/CD274 from being polyubiquitinated and targeted for degradation. |
| Protein Name | Cklf-Like Marvel Transmembrane Domain-Containing Protein 4Chemokine-Like Factor Superfamily Member 4 |
| Database Links | |
| Cellular Localisation | MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Cklf-Like Marvel Transmembrane Domain-Containing Protein 4 antibodyAnti-Chemokine-Like Factor Superfamily Member 4 antibodyAnti-CMTM4 antibodyAnti-CKLFSF4 antibody |
Information sourced from Uniprot.org