• Western blot analysis of CKLF4 Antibody. The lane on the right is blocked with the CKLF4 peptide.
  • Immunohistochemistryt analysis of paraffin-embedded human breast carcinoma, using CKLF4 Antibody. The lane on the right is blocked with the CKLF4 peptide.
  • Western blot analysis of HELA cells using CMTM4 Polyclonal Antibody

Anti-CMTM4 antibody (161-210 aa) (STJ92351)

SKU:
STJ92351

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-CKLF-like MARVEL transmembrane domain-containing protein 4 (161-210 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC-P 1:100-300
ELISA 1:20000
IF 1:100-300
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CMTM4
Gene ID: 146223
Uniprot ID: CKLF4_HUMAN
Immunogen Region: 161-210 aa
Specificity: CMTM4 Polyclonal Antibody detects endogenous levels of CMTM4 protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human CKLF4 at the amino acid range 161-210
Function Acts as a backup for CMTM6 to regulate plasma membrane expression of PD-L1/CD274, an immune inhibitory ligand critical for immune tolerance to self and antitumor immunity. May protect PD-L1/CD274 from being polyubiquitinated and targeted for degradation.
Protein Name Cklf-Like Marvel Transmembrane Domain-Containing Protein 4
Chemokine-Like Factor Superfamily Member 4
Cellular Localisation Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Cklf-Like Marvel Transmembrane Domain-Containing Protein 4 antibody
Anti-Chemokine-Like Factor Superfamily Member 4 antibody
Anti-CMTM4 antibody
Anti-CKLFSF4 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance