Immunofluorescence analysis of Jurkat cells using CD66b/CEACAM8 Rabbit pAb (STJ11100946) at dilution of 1:100. Secondary antibody: Cy3-conjugated Goat anti-Rabbit IgG (H+L) (STJS001166) at 1:500 dilution. Blue: DAPI for nuclear staining.

Anti-CEACAM8 antibody (35-320) (STJ11100946)

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STJ11100946
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Applications:WB/IF/ICC/ELISA
Host:Rabbit
Reactivity:Human
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Polyclonal
Isotype:IgG
Conjugation:Unconjugated
Concentration:Lot specific
Purification:Affinity purification
Dilution Range:WB:1:500-1:2000
IF/ICC:1:50-1:200
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Formulation:PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3.
Storage Instruction:Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol:CEACAM8
Gene ID:1088
Uniprot ID:CEAM8_HUMAN
Immunogen Region:35-320
Immunogen Sequence:QLTIEAVPSNAAEGKEVLLL VHNLPQDPRGYNWYKGETVD ANRRIIGYVISNQQITPGPA YSNRETIYPNASLLMRNVTR NDTGSYTLQVIKLNLMSEEV TGQFSVHPETPKPSISSNNS NPVEDKDAVAFTCEPETQNT TYLWWVNGQSLPVSPRLQLS NGNRTLTLLSVTRNDVGPYE CEIQNPASANFSDPVTLNVL YGPDAPTISPSDTYYHAGVN LNLSCHAASNPPSQYSWSV
Specificity:Recombinant fusion protein containing a sequence corresponding to amino acids 35-320 of human CD66b/CEACAM8 (NP_001807.2).
Tissue Specificity Expressed in leukocytes of chronic myeloid Leukemia patients and bone marrow.
Post Translational Modifications Glycosylated.
Function Cell surface glycoprotein that plays a role in cell adhesion in a calcium-independent manner. Mediates heterophilic cell adhesion with other carcinoembryonic antigen-related cell adhesion molecules, such as CEACAM6. Heterophilic interaction with CEACAM8 occurs in activated neutrophils.
Protein Name Cell Adhesion Molecule Ceacam8
Cd67 Antigen
Carcinoembryonic Antigen Cgm6
Carcinoembryonic Antigen-Related Cell Adhesion Molecule 8
Cea Cell Adhesion Molecule 8
Non-Specific Cross-Reacting Antigen Nca-95
Cd Antigen Cd66b
Database Links Reactome: R-HSA-1566977
Reactome: R-HSA-202733
Reactome: R-HSA-6798695
Cellular Localisation Cell Membrane
Lipid-Anchor
Gpi-Anchor
Cell Surface
Alternative Antibody Names Anti-Cell Adhesion Molecule Ceacam8 antibody
Anti-Cd67 Antigen antibody
Anti-Carcinoembryonic Antigen Cgm6 antibody
Anti-Carcinoembryonic Antigen-Related Cell Adhesion Molecule 8 antibody
Anti-Cea Cell Adhesion Molecule 8 antibody
Anti-Non-Specific Cross-Reacting Antigen Nca-95 antibody
Anti-Cd Antigen Cd66b antibody
Anti-CEACAM8 antibody
Anti-CGM6 antibody

Information sourced from Uniprot.org

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