Anti-CEACAM8 antibody (35-320) (STJ11100946)

Name: Anti-CEACAM8 antibody (35-320) (STJ11100946)
SKU: STJ11100946
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⇓ Datasheet ⇓ SDS

SPECIFICATIONS

ClonalityPolyclonal

HostRabbit

ConjugationUnconjugated

IsotypeIgG

STJ11100946

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Short Description	Rabbit polyclonal CEACAM8 (35-320) antibody for use in WB, IF, ICC and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents.
Applications	WB/IF/ICC/ELISA
Host	Rabbit
Reactivity	Human
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Polyclonal
Isotype	IgG
Conjugation	Unconjugated
Concentration	Lot specific
Purification	Affinity purification
Dilution Range	WB:1:500-1:2000 IF/ICC:1:50-1:200 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Formulation	PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3.
Storage Instruction	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol	CEACAM8
Gene ID	1088
Uniprot ID	CEAM8_HUMAN
Immunogen Region	35-320
Immunogen Sequence	QLTIEAVPSNAAEGKEVLLL VHNLPQDPRGYNWYKGETVD ANRRIIGYVISNQQITPGPA YSNRETIYPNASLLMRNVTR NDTGSYTLQVIKLNLMSEEV TGQFSVHPETPKPSISSNNS NPVEDKDAVAFTCEPETQNT TYLWWVNGQSLPVSPRLQLS NGNRTLTLLSVTRNDVGPYE CEIQNPASANFSDPVTLNVL YGPDAPTISPSDTYYHAGVN LNLSCHAASNPPSQYSWSV
Specificity	Recombinant fusion protein containing a sequence corresponding to amino acids 35-320 of human CD66b/CEACAM8 (NP_001807.2).

Tissue Specificity	Expressed in leukocytes of chronic myeloid Leukemia patients and bone marrow.
Post Translational Modifications	Glycosylated.
Function	Cell surface glycoprotein that plays a role in cell adhesion in a calcium-independent manner. Mediates heterophilic cell adhesion with other carcinoembryonic antigen-related cell adhesion molecules, such as CEACAM6. Heterophilic interaction with CEACAM8 occurs in activated neutrophils.
Protein Name	Cell Adhesion Molecule Ceacam8 Cd67 Antigen Carcinoembryonic Antigen Cgm6 Carcinoembryonic Antigen-Related Cell Adhesion Molecule 8 Cea Cell Adhesion Molecule 8 Non-Specific Cross-Reacting Antigen Nca-95 Cd Antigen Cd66b
Database Links	Reactome: R-HSA-1566977 Reactome: R-HSA-202733 Reactome: R-HSA-6798695
Cellular Localisation	Cell Membrane Lipid-Anchor Gpi-Anchor Cell Surface
Alternative Antibody Names	Anti-Cell Adhesion Molecule Ceacam8 antibody Anti-Cd67 Antigen antibody Anti-Carcinoembryonic Antigen Cgm6 antibody Anti-Carcinoembryonic Antigen-Related Cell Adhesion Molecule 8 antibody Anti-Cea Cell Adhesion Molecule 8 antibody Anti-Non-Specific Cross-Reacting Antigen Nca-95 antibody Anti-Cd Antigen Cd66b antibody Anti-CEACAM8 antibody Anti-CGM6 antibody

Information sourced from Uniprot.org