| Short Description : | Rabbit polyclonal CEACAM8 (35-320) antibody for use in WB, IF, ICC and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/IF/ICC/ELISA |
| Host: | Rabbit |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CEACAM8 |
| Gene ID: | 1088 |
| Uniprot ID: | CEAM8_HUMAN |
| Immunogen Region: | 35-320 |
| Immunogen Sequence: | QLTIEAVPSNAAEGKEVLLL VHNLPQDPRGYNWYKGETVD ANRRIIGYVISNQQITPGPA YSNRETIYPNASLLMRNVTR NDTGSYTLQVIKLNLMSEEV TGQFSVHPETPKPSISSNNS NPVEDKDAVAFTCEPETQNT TYLWWVNGQSLPVSPRLQLS NGNRTLTLLSVTRNDVGPYE CEIQNPASANFSDPVTLNVL YGPDAPTISPSDTYYHAGVN LNLSCHAASNPPSQYSWSV |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 35-320 of human CD66b/CEACAM8 (NP_001807.2). |
| Tissue Specificity | Expressed in leukocytes of chronic myeloid Leukemia patients and bone marrow. |
| Post Translational Modifications | Glycosylated. |
| Function | Cell surface glycoprotein that plays a role in cell adhesion in a calcium-independent manner. Mediates heterophilic cell adhesion with other carcinoembryonic antigen-related cell adhesion molecules, such as CEACAM6. Heterophilic interaction with CEACAM8 occurs in activated neutrophils. |
| Protein Name | Cell Adhesion Molecule Ceacam8Cd67 AntigenCarcinoembryonic Antigen Cgm6Carcinoembryonic Antigen-Related Cell Adhesion Molecule 8Cea Cell Adhesion Molecule 8Non-Specific Cross-Reacting Antigen Nca-95Cd Antigen Cd66b |
| Database Links | Reactome: R-HSA-1566977Reactome: R-HSA-202733Reactome: R-HSA-6798695 |
| Cellular Localisation | Cell MembraneLipid-AnchorGpi-AnchorCell Surface |
| Alternative Antibody Names | Anti-Cell Adhesion Molecule Ceacam8 antibodyAnti-Cd67 Antigen antibodyAnti-Carcinoembryonic Antigen Cgm6 antibodyAnti-Carcinoembryonic Antigen-Related Cell Adhesion Molecule 8 antibodyAnti-Cea Cell Adhesion Molecule 8 antibodyAnti-Non-Specific Cross-Reacting Antigen Nca-95 antibodyAnti-Cd Antigen Cd66b antibodyAnti-CEACAM8 antibodyAnti-CGM6 antibody |
Information sourced from Uniprot.org
