Anti-CCT2 antibody (206-535) (STJ28629)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal CCT2 (206-535) antibody for use in WB, IF, ICC, IP and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/IP/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IF/ICC:1:50-1:200IP:0.5 Mu g-4 Mu g antibody for 200 Mu g-400 Mu g extracts of whole cellsELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements |
| Formulation | PBS with 0.09% Sodium Azide, 50% Glycerol, pH7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CCT2 |
| Gene ID | 10576 |
| Uniprot ID | TCPB_HUMAN |
| Immunogen Region | 206-535 |
| Immunogen Sequence | GGSLADSYLDEGFLLDKKIG VNQPKRIENAKILIANTGMD TDKIKIFGSRVRVDSTAKVA EIEHAEKEKMKEKVERILKH GINCFINRQLIYNYPEQLFG AAGVMAIEHADFAGVERLAL VTGGEIASTFDHPELVKLGS CKLIEEVMIGEDKLIHFSGV ALGEACTIVLRGATQQILDE AERSLHDALCVLAQTVKDSR TVYGGGCSEMLMAHAVTQLA NRTPGKEAVAMESYAKALR |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 206-535 of human TCP1 beta/TCP1 beta/CCT2 (NP_006422.1). |
Additional Info
| Function | Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of actin, tubulin and other proteins upon ATP hydrolysis. The TRiC complex mediates the folding of WRAP53/TCAB1, thereby regulating telomere maintenance. As part of the TRiC complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. |
| Protein Name | T-Complex Protein 1 Subunit BetaTcp-1-BetaCct-BetaChaperonin Containing T-Complex Polypeptide 1 Subunit 2 |
| Database Links | Reactome: R-HSA-389957Reactome: R-HSA-389960Reactome: R-HSA-390450Reactome: R-HSA-390471Reactome: R-HSA-5620922Reactome: R-HSA-6798695Reactome: R-HSA-6814122Reactome: R-HSA-9013418Reactome: R-HSA-9013422 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-T-Complex Protein 1 Subunit Beta antibodyAnti-Tcp-1-Beta antibodyAnti-Cct-Beta antibodyAnti-Chaperonin Containing T-Complex Polypeptide 1 Subunit 2 antibodyAnti-CCT2 antibodyAnti-99D8.1 antibodyAnti-CCTB antibody |
Information sourced from Uniprot.org