Anti-CCDC115 antibody (STJA0008960)

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:	1 mg/mL
Dilution Range:	WB 1:500-2000
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	CCDC115
Gene ID:	84317
Uniprot ID:	CC115_HUMAN
Specificity:	This antibody detects endogenous levels of CCDC115 at Human, Mouse
Immunogen:	Synthesized peptide derived from human CCDC115

Function	Accessory component of the proton-transporting vacuolar (V)-ATPase protein pump involved in intracellular iron homeostasis. In aerobic conditions, required for intracellular iron homeostasis, thus triggering the activity of Fe(2+) prolyl hydroxylase (PHD) enzymes, and leading to HIF1A hydroxylation and subsequent proteasomal degradation. Necessary for endolysosomal acidification and lysosomal degradation. May be involved in Golgi homeostasis.
Protein Name	Coiled-Coil Domain-Containing Protein 115
Database Links	Reactome: R-HSA-8980692
Cellular Localisation	Endosome Lysosome Endoplasmic Reticulum-Golgi Intermediate Compartment Cytoplasmic Vesicle Copi-Coated Vesicle Endoplasmic Reticulum
Alternative Antibody Names	Anti-Coiled-Coil Domain-Containing Protein 115 antibody Anti-CCDC115 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance