Anti-CCDC115 antibody (STJA0008960)

Name: Anti-CCDC115 antibody (STJA0008960)
SKU: STJA0008960
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

ClonalityPolyclonal

HostRabbit

ConjugationUnconjugated

IsotypeIgG

ImmunogenSynthesized peptide derived from human CCDC115

STJA0008960

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Short Description	Rabbit polyclonal anti-Coiled-coil domain-containing protein 115 for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents.
Applications	WB
Host	Rabbit
Reactivity	Human/Mouse
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Polyclonal
Isotype	IgG
Conjugation	Unconjugated
Concentration	1 mg/mL
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Dilution Range	WB 1:500-2000
Formulation	Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage Instruction	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol	VMA22
Gene ID	84317
Uniprot ID	VMA22_HUMAN
Immunogen	Synthesized peptide derived from human CCDC115
Specificity	This antibody detects endogenous levels of CCDC115 at Human, Mouse

Function	Accessory component of the proton-transporting vacuolar (V)-ATPase protein pump involved in intracellular iron homeostasis. In aerobic conditions, required for intracellular iron homeostasis, thus triggering the activity of Fe(2+) prolyl hydroxylase (PHD) enzymes, and leading to HIF1A hydroxylation and subsequent proteasomal degradation. Necessary for endolysosomal acidification and lysosomal degradation. May be involved in Golgi homeostasis.
Protein Name	Vacuolar Atpase Assembly Protein Vma22 Coiled-Coil Domain-Containing Protein 115
Database Links	Reactome: R-HSA-8980692
Cellular Localisation	Endosome Lysosome Endoplasmic Reticulum-Golgi Intermediate Compartment Cytoplasmic Vesicle Copi-Coated Vesicle Endoplasmic Reticulum
Alternative Antibody Names	Anti-Vacuolar Atpase Assembly Protein Vma22 antibody Anti-Coiled-Coil Domain-Containing Protein 115 antibody Anti-VMA22 antibody Anti-CCDC115 antibody

Information sourced from Uniprot.org