| Host: |
Rabbit |
| Applications: |
WB/IHC |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Caspase-12 (200-300) is suitable for use in Western Blot and Immunohistochemistry research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.05% Proclin300, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:1000IHC-P 1:50-1:200 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
CASP12 |
| Gene ID: |
100506742 |
| Uniprot ID: |
CASPC_HUMAN |
| Immunogen Region: |
200-300 |
| Immunogen: |
A synthetic peptide corresponding to a sequence within amino acids 200-300 of human Caspase-12 (NP_001177945.2). |
| Immunogen Sequence: |
FNNRNCQSLKDKPKVIIMQA CRGNGAGIVWFTTDSGKASA DTHGRLLQGNICNDAVTKAH VEKDFIAFKSSTPHNVSWRH ETNGSVFISQIIYYFREYSW S |
| Tissue Specificity | Widely expressed, with highest levels in lung. |
| Function | May function as a negative regulator of inflammatory responses and innate immunity. May reduce cytokine release in response to bacterial lipopolysaccharide during infection. Reduces activation of NF-kappa-B in response to TNF. May lack protease activity (Probable). |
| Protein Name | Inactive Caspase-12Casp-12 |
| Alternative Antibody Names | Anti-Inactive Caspase-12 antibodyAnti-Casp-12 antibodyAnti-CASP12 antibodyAnti-UNQ9415 antibodyAnti-PRO34398 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
