Anti-CAND2 antibody (850-1000) (STJ118927)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal CAND2 (850-1000) antibody for use in WB, IHC-P and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CAND2 |
| Gene ID | 23066 |
| Uniprot ID | CAND2_HUMAN |
| Immunogen Region | 850-1000 |
| Immunogen Sequence | VGQVAGPGHQRELKAVLLEA LGSPSEDVRAAASYALGRVG AGSLPDFLPFLLEQIEAEPR RQYLLLHSLREALGAAQPDS LKPYAEDIWALLFQRCEGAE EGTRGVVAECIGKLVLVNPS FLLPRLRKQLAAGRPHTRST VITAVKFLISD |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 850-1000 of human CAND2 (NP_001155971.1). |
Additional Info
| Tissue Specificity | Expressed in epididymis (at protein level). |
| Post Translational Modifications | Ubiquitinated and targeted for proteasomal degradation. |
| Function | Probable assembly factor of SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complexes that promotes the exchange of the substrate-recognition F-box subunit in SCF complexes, thereby playing a key role in the cellular repertoire of SCF complexes. |
| Protein Name | Cullin-Associated Nedd8-Dissociated Protein 2Cullin-Associated And Neddylation-Dissociated Protein 2Epididymis Tissue Protein Li 169Tbp-Interacting Protein Of 120 Kda BTbp-Interacting Protein 120bP120 Cand2 |
| Database Links | |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Cullin-Associated Nedd8-Dissociated Protein 2 antibodyAnti-Cullin-Associated And Neddylation-Dissociated Protein 2 antibodyAnti-Epididymis Tissue Protein Li 169 antibodyAnti-Tbp-Interacting Protein Of 120 Kda B antibodyAnti-Tbp-Interacting Protein 120b antibodyAnti-P120 Cand2 antibodyAnti-CAND2 antibodyAnti-KIAA0667 antibodyAnti-TIP120B antibody |
Information sourced from Uniprot.org