| Short Description : | Rabbit polyclonal CAND2 (850-1000) antibody for use in WB, IHC-P and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/IHC-P/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:2000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CAND2 |
| Gene ID: | 23066 |
| Uniprot ID: | CAND2_HUMAN |
| Immunogen Region: | 850-1000 |
| Immunogen Sequence: | VGQVAGPGHQRELKAVLLEA LGSPSEDVRAAASYALGRVG AGSLPDFLPFLLEQIEAEPR RQYLLLHSLREALGAAQPDS LKPYAEDIWALLFQRCEGAE EGTRGVVAECIGKLVLVNPS FLLPRLRKQLAAGRPHTRST VITAVKFLISD |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 850-1000 of human CAND2 (NP_001155971.1). |
| Tissue Specificity | Expressed in epididymis (at protein level). |
| Post Translational Modifications | Ubiquitinated and targeted for proteasomal degradation. |
| Function | Probable assembly factor of SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complexes that promotes the exchange of the substrate-recognition F-box subunit in SCF complexes, thereby playing a key role in the cellular repertoire of SCF complexes. |
| Protein Name | Cullin-Associated Nedd8-Dissociated Protein 2Cullin-Associated And Neddylation-Dissociated Protein 2Epididymis Tissue Protein Li 169Tbp-Interacting Protein Of 120 Kda BTbp-Interacting Protein 120bP120 Cand2 |
| Database Links | |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Cullin-Associated Nedd8-Dissociated Protein 2 antibodyAnti-Cullin-Associated And Neddylation-Dissociated Protein 2 antibodyAnti-Epididymis Tissue Protein Li 169 antibodyAnti-Tbp-Interacting Protein Of 120 Kda B antibodyAnti-Tbp-Interacting Protein 120b antibodyAnti-P120 Cand2 antibodyAnti-CAND2 antibodyAnti-KIAA0667 antibodyAnti-TIP120B antibody |
Information sourced from Uniprot.org
